Overview Chromocell’s Chromovert® Technology overcomes the fundamental obstacle to effective cell-based screening: Creation of a high throughput assay that reliably predicts efficacy. By efficiently identifying and isolating one out of millions of analyzed cells, we are able to identify rare clones, stably expressing multiple untagged genes of interest that comprise a complete physiologically relevant target. Starting with more relevant cells allows for high-throughput screening with unparalleled results.
Chromocell is engaged in the discovery and development of therapeutic compounds against the most complex and challenging drug targets. We focus on projects that require multi-gene cell lines or large panels of related receptors, where the use of Chromovert technology provides a competitive advantage.
We have integrated drug discovery and development capabilities with laboratories in North Brunswick, NJ. Our discovery resources span hit identification through IND-enabling studies, including molecular and cellular biology, assay development, high-throughput screening, medicinal, natural product and analytical chemistry and in vivo pharmacology.
Drug development at Chromocell includes all the expertise necessary to conduct clinical trials and satisfy requirements for marketing authorizations, including expertise in drug substance and product manufacturing, toxicology, regulatory, and clinical operations.